TNF-alpha Antibody MAB210-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemTNF-alpha Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB210-100
ConcentrationLYOPH
PurityProtein A or G purified from ascites
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
ReactivityHuman (Hu)
ClonalityMonoclonal
NCBI Gene AliasesTNFSF2, DIF, TNF-alpha, TNLG1F, TNFA
NCBI Full Gene Nametumor necrosis factor
ApplicationsNeutralize (Neut)
ImmunogenE. coli-derived recombinant human TNF-alpha, Gly57-Leu233, Accession # P01375
HostMouse
Clone1825
IsotypeIgG1
TargetTNF-alpha
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Conjugate/TagUnconjugated
Quantity100 ug (also 500 ug, 25 ug)

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human TNF-alpha in direct ELISAs. In direct ELISAs, approximately 50% cross-reactivity with recombinant rhesus macaque TNF-alpha is observed and no cross-reactivity with recombinant cotton rat, mouse, rat, or porcine TNF-alpha is observed. It shows no cross-reactivity with recombinant human (rh) APRIL, rhBAFF, rhEDA-A2, rhFas Ligand, rhGITR Ligand, rhLIGHT, rhOX40 Ligand, rhRANK Ligand, rhTNF-beta, rhTRAIL, rhTRANCE, rhTWEAK, or rhVEGI

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Targeting hypoxia-induced tumor stemness by activating pathogen-induced stem cell niche defenseFrontiers in immunologyJanuary 1, 2022Bhuyan S, Pal B, Pathak L, Saikia PJ, Mitra S, Gayan S, Mokhtari RB, Li H, Ramana CV, Baishya D, et al.

(2) Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic CellsFrontiers in immunologyJanuary 1, 2021Gu C, Upchurch K, Horton J, Wiest M, Zurawski S, Millard M, Kane RR, Joo H, Miller LA, Oh S.anti-IL-10R (BioLegend, 308817), isotype control rat IgG2a (BioLegend, 400543), anti-TNFα (R&D Systems, MAB210-100) or isotype control mouse IgG1 (BioLegend, 400166) was added into culture 1h or 3h before stimulation.

(3) NF-κB-dependent miR-31/155 biogenesis is essential for TNF-α-induced impairment of endothelial progenitor cell functionExperimental & molecular medicineAugust 1, 2020Kim JH, Kim JY, Park M, Kim S, Kim T, Kim J, Choi S, Park W, Hwang JY, Choe J, et al.

(4) Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1Nature communicationsJuly 10, 2020Sellau J, Groneberg M, Fehling H, Thye T, Hoenow S, Marggraff C, Weskamm M, Hansen C, Stanelle-Bertram S, Kuehl S, et al.

(5) HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune EnhancersCell chemical biologyMarch 21, 2019Mo X, Tang C, Niu Q, Ma T, Du Y, Fu H.instruction. The human TNFα neutralization mouse monoclonal antibody was purchased from R&D Systems (#MAB210-100). The human IFNγ neutralization mouse monoclonal antibody and mouse IgG1 isotype control were purchased

(6) Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airwaysPLoS pathogensSeptember 1, 2017Reuschl AK, Edwards MR, Parker R, Connell DW, Hoang L, Halliday A, Jarvis H, Siddiqui N, Wright C, Bremang S, et al.

(7) Chitosan oligosaccharide improves the therapeutic efficacy of sitagliptin for the therapy of Chinese elderly patients with type 2 diabetes mellitusTherapeutics and Clinical Risk ManagementJuly 20, 2017Lijie Zhao, Tingli Sun, Lina Wangwere disrupted by hypotonic lysis in sterile water. Human CRP antibody AF1707, human TNF-α antibody MAB210-100, human adiponectin/Acrp30 antibody (AF1065), human resistin antibody MAB13591-100, and human GAPDH antibody

(8) Antigen delivery to dendritic cells shapes human CD4+ and CD8+ T cell memory responses to Staphylococcus aureusPLoS pathogensMay 1, 2017Uebele J, Stein C, Nguyen MT, Schneider A, Kleinert F, Tichá O, Bierbaum G, Götz F, Bekeredjian-Ding I.

(9) A polysaccharide virulence factor of a human fungal pathogen induces neutrophil apoptosis via NK cellsJournal of immunology (Baltimore, Md. : 1950)June 1, 2014Robinet P, Baychelier F, Fontaine T, Picard C, Debré P, Vieillard V, Latgé JP, Elbim C.

(10) Activin A as a mediator of NK-dendritic cell functional interactionsJournal of immunology (Baltimore, Md. : 1950)February 1, 2014Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, Sozzani S.

(11) Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formationPloS oneJanuary 1, 2012Nicolaidou V, Wong MM, Redpath AN, Ersek A, Baban DF, Williams LM, Cope AP, Horwood NJ.

(12) IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generationPLoS biologyJanuary 1, 2012Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, Hoppe E, Barré B, Audran M, Bouvard B, et al.

(13) KiSS1 metastasis suppressor gene product induces suppression of tyrosine kinase receptor signaling to Akt, tumor necrosis factor family ligand expression, and apoptosisMolecular pharmacologyMay 1, 2009Navenot JM, Fujii N, Peiper SC.

(14) Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayersDigestive diseases and sciencesOctober 1, 2007van Grevenstein WM, Hofland LJ, van Rossen ME, van Koetsveld PM, Jeekel J, van Eijck CH.

(15) Peroxisome proliferator-activated receptor-gamma agonists inhibit respiratory syncytial virus-induced expression of intercellular adhesion molecule-1 in human lung epithelial cellsImmunologyMay 1, 2007Arnold R, Neumann M, König W.

(16) Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropeniaExperimental hematologyOctober 1, 2006Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos GD, Papadaki HA.

(17) Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcriptionCellular immunologyMay 1, 2006Ebert EC, Mehta V.

(18) Effect of cognate human CD4+ T cell and endothelial cell interactions upon chemokine productionTransplantationOctober 15, 2004Tay SS, McCormack A, Rose ML.

(19) A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseasesJournal of leukocyte biologyOctober 1, 2001Albanesi C, Scarponi C, Sebastiani S, Cavani A, Federici M, Sozzani S, Girolomoni G.

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TNF-alpha Antibody

TNF-alpha Antibody

TNF-alpha Antibody

TNF-alpha Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (19)

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TNF-alpha Antibody from R&D Systems, a Bio-Techne Brand

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